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Similarly, Eric Polley, PhD, a UChicago data science and public health expert, recently led a study published in Nature Cardiovascular Research that used statistical modeling to emulate a clinical trial comparing the effects of four different classes of diabetes medication in patients with moderate cardiovascular risk

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This is an important and evolving topic
Laboratory studies can show receptor interactions but cannot fully represent a complete organism
In patients at high risk of developing antecedent diabetes and/or metabolic syndrome, weight loss is effective in preventing progression to type 2 diabetes mellitus (T2DM) and improving cardiovascular risk factors [12]
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