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Both are excellent once weekly injections, but they aren't quite the same medication. Wegovy contains semaglutide and works on GLP1 alone, with an average weight loss of around 15% in trials. Mounjaro contains tirzepatide and works on two hormones (GLP1 and GIP), with an average weight loss of 22.5%. Wegovy starts from 99.99 a month and Mounjaro from 164.99. Your clinician will help you decide which is the better fit for your goals, medical history, and budget
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Get the most up-to-date information on semaglutide costs in 2026
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