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female: n = 27,708)

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Thyroid C-Cell Tumors: In mice and rats, tirzepatide (the active ingredient in Zepbound and Mounjaro) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)
This means using Wegovy after a sleeve falls outside the original STEP trial evidence base
The cohort had a median diabetes duration of 10.0 years, with a baseline median HbA1c of 7.7%

doi: 10.1152/ajpendo.1999.276.6.E1049
