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It is given as a once-weekly subcutaneous injection and is indicated for adults with a BMI of 30 or higher, or 27 or higher with at least one weight-related condition such as hypertension, high cholesterol, or type 2 diabetes

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Months 5 and 6 typically show either continued steady progress or a slight plateauboth outcomes are normal and expected

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The activation of NF-B may lead to elevated androgen levels and disrupted glucose and lipid metabolism in PCOS patients.57 Inhibiting the NF-B-mediated inflammatory signaling pathway significantly improves the ovarian hormone microenvironment in PCOS rats.58 In line with these studies, the expression of TNF-, IL-6, and IL-1 NF-B increased in the ovaries of PCOS mice
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