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Semaglutide (s.c.) has shown greater efficacy in reducing body weight as compared to placebo and liraglutide in STEP trials

But it does even more

However, one expert is warning users against making any sudden switches, as it may not work out well for them

We dont know that yet. Whats ahead Rosenthal at Cleveland Clinic Florida says he likes having these drugs in his toolbox

Baseline liver function testing before starting semaglutide and periodic monitoring during treatment is standard clinical practice

Abbreviations DM2: diabetes mellitus type 2 GCR: glucagon receptor GIPR: glucose-dependent insulinotropic peptide receptor GLP-1a: glucagon-like peptide-1 analogues HbA1c: glycated hemoglobin HCC: hepatocellular carcinoma MRI-PDFF: Magnetic Resonance Imaging-Proton Density Fat Fraction NAFLD: Non-alcoholic fatty liver disease NASH: non-alcoholic steatohepatitis NCT: National Clinical Trial number PPAR: Peroxisome Proliferator-Activated Receptor RCT: randomized clinical trial SGLT-2i: sodium-glucose co-transporter-2 inhibitors Declarations Funding None to declare