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Metformin was the most common oral glucose-lowering therapy used, totalling 43% of all patients who were prescribed adjunctive therapies

Constipation occurs in some individuals due to slowed gastrointestinal transit, while others may experience loose stools or diarrhea

Taken together, these results strongly suggest that curcumin acts as an agonist for GPR55

doi: 10.1016/S0140-6736(19)31149-3 71 RomeraICebrian-CuencaAAlvarez-GuisasolaFGomez-PeraltaFReviriegoJ

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