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Global, regional, and national burden of gout, 1990-2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021

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Midler et al

These microbiome alterations are associated with greater intestinal barrier integrity, decreased endotoxemia, and increased synthesis of short-chain fatty acids

BCTC is also a potent antagonist of TRPV1 activated by protons 45
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