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Sources: Wharton S, Lingvay I, Bogdanski P, et al

However, retatrutide has not yet received marketing authorisation from the MHRA or EMA, meaning it is not currently available as a licensed medicine in the UK

[10] [11] Based on data from retatrutide clinical trials (NEJM, 2023) and experience with similar approved agents, patients may experience: Redness, swelling, or itching at the injection site, which typically resolves within a few hours to days Bruising or mild pain immediately following injection Nodules or localised reactions beneath the skin, which may occur with repeated injections at the same site These reactions are generally mild and self-limiting

[17] These receptors are predominantly found in the suprachiasmatic nucleus of the hypothalamus, which serves as the bodys master circadian clock, as well as in various other brain regions including the hippocampus, cortex, and brainstem

Semaglutide, a medication primarily used to treat type 2 diabetes, has been gaining attention for its effectiveness in this area

Increasing feelings of fullness - Semaglutide seems to enhance the stretch receptors in your stomach that signal when you've eaten enough