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Tracking how long it takes for appetite suppression to develop requires self-reporting, not lab work

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More than a year later, in September 2013, the regulator rejected the application, asking the company to perform another well-controlled randomized trial to better determine the safety and efficacy of the investigational product

doi:10.1017/S0007114513002912 Sesso HD, Manson JE, Aragaki AK, et al

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For folks who are new to the show, this is borrowed from our great friend, Hamilton Helmer and his wonderful book, Seven Powers, where he talks about the means by which a company can achieve persistent differential positive returns versus their competitors in an industry