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It signals to the brain that food has arrived, slows gastric emptying so nutrients absorb more gradually, and stimulates insulin release in a glucose-dependent manner

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key role of GLP-1R

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In addition to improved glycemic control, Nakamura et al

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And this creates an enormous opportunity

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GLP-1 agonist Liraglutide prevents MK801-induced schizophrenialike behaviors and BDNF, CREB, p-CREB, Trk-B expressions in the hippocampus and prefrontal cortex in Balb/c mice

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Molecular Metabolism 65101586

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