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Some users report that taking their injection in the morning rather than evening reduces nighttime GI discomfort and sleep disruption

If youve been reading this newsletter, you know Ive written about the fact that OA patients on GLP-1 drugs report pain improvement long before any meaningful weight loss occurs

doi: 10.1212/WNL.0000000000005771, PMID: [DOI] [PubMed] [Google Scholar] 11.Schernhammer E, Hansen J, Rugbjerg K, Wermuth L, Ritz B

and combination: 48 17 vs

Semaglutide 2.4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): A randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

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