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Interestingly, certain bitter compounds, such as denatonium benzoate (DB), have been found to stimulate the secretion of insulin, glucagon, somatostatin, and GLP-1 from pancreatic islets independently of glucose levels

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Only a quarter of patients remained on any particular GLP-1 drug a year after starting it, and roughly 1 in 5 patients transitioned to a different weight-loss med during that period, researchers said

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Moreover, about 9 in 10 Americans are aware that the drugs are available for weight loss, up from 8 in 10 in 2024