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Testing can reveal whether a patient genetically favors dopamine-driven approaches (bupropion's strength) or gut-hormone-driven approaches (semaglutide's mechanism), helping clinicians design truly personalized dual therapy

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Furthermore, increases in GIP are seen with HFD consumption in humans and rodents

Additionally, low-income neighborhoods, which are disproportionately home to Black and Hispanic populations, often lack the healthcare infrastructure and pharmacy access necessary to obtain these medications