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Autophagy regulates lipid metabolism

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[28,29] Furthermore, surgery is not considered the first line of treatment for everyone because it requires patients to meet the eligibility criteria, which include a BMI 40, the presence of one or more obesity-related comorbidities (heart disease, stroke, hypertension, and T2D), and the inability to maintain a healthy weight over time

For all the lipidated analogues studied, ANS curves start from nonzero values (Figure 4B,D,F,H), which indicates binding of ANS to oligomeric species and/or to the hydrophobic lipid moiety itself

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