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A substudy examining participants with metabolic-associated steatotic liver disease produced results that no pharmacological intervention had previously achieved

once-weekly in type 2 diabetes: a population pharmacokinetic analysis
Key Points The rate of gastric emptying is a critical determinant of postprandial glycaemia Disordered gastric emptying is common in patients with longstanding type 1 diabetes mellitus and type 2 diabetes mellitus

Some small studies, they note, have suggested that exercise can help improve VO 2 max for patients taking GLP-1 drugs, but these had poor controls and larger, well-designed studies are needed to bear that out
