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Always follow a healthcare professionals guidance when considering multiple treatments
Tirzepatide remained the leading AOM and ADM by prescription volume and showed the largest increase in total prescribing from September to December 2025
Srivastava and Ali say those findings generally align with what they see in practice

Elizabeth McDonald, M.D., Ph.D

Psychosocial factors, such as early trauma or chronic stress, can also play a role in non-response to semaglutide

Drinking more water, increasing fiber intake, and staying physically active may help reduce symptoms
