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The dosage of saxagliptin is 2.5 mg once daily when co-administered with a strong cytochrome P450 3A4/5 inhibitor (e.g., ketoconazole, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin) (package insert)

If patients experience intolerable side effects at a given dose, maintaining the current dose for an additional 4 weeks or temporarily reducing the dose may improve tolerance before attempting further escalation

Coverage depends on the specific plan and formulary

Lifestyle and Other Interactions Alcohol Consumption : Gabapentins CNS depressant effects are significantly increased by alcohol

Patients should review their plans formulary, confirm prior authorization rules, and explore manufacturer assistance programs before starting treatment

PlexusDx recommends varying your injection site each week, rotating between both upper arms, abdomen, and thighs in a planned pattern