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Completion of the trials main phase is expected in September 2025, and the 52-week extension (in which participants and investigators remain blinded to treatment assignment) will continue to October 2026

Semaglutide is a drug that has received a lot of attention for its ability to help people lose weight

The study compared three types of the medication: tirzepatide (better known under the brand names Zepbound and Mounjaro), semaglutide (sold as Wegovy and Ozempic), and liraglutide (aka Saxenda and Victoza).

The incidence of DS was reported between 9 to 42.9% and 0.5% to 27.8% in studies using the Sigstad dumping score and patients self-reported DS, respectively

Benefit of semaglutide vs placebo additionally supported by statistically significant improvement in liver stiffness measurement by VCTE (FibroScan Echosens)

In an investigative report in partnership with KFF Health News, NBC News Anne Thompson reports on the growing cases of overdoses involving GLP-1 weight loss drugs.