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Glucagon-like peptide 1 and its analogs act in the dorsal raphe and modulate central serotonin to reduce appetite and body weight
doi: 10.1007/s00125-018-4729-5
Additionally, 86.6% of those treated with semaglutide achieved a 5% reduction in bodyweight, compared with 47.6% of those receiving placebo
71 Furthermore, GLP-1RA has been investigated for its potential to reduce the risk of cardiovascular events in patients with or without diabetes
A 2024 meta-analysis found GLP-1 receptor agonists helped lower BMI, waist circumference, triglycerides, and total testosterone in women with PCOS living with obesity
Holst JJ, Knop FK, Vilsbll T, Krarup T, Madsbad S
