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95% CI, 0.63-0.96), but there was no difference between oral semaglutide and placebo in patients without prior HF (HR = 1.01

This article examines the current evidence regarding any potential relationship between GLP-1 therapy and cortisol regulation, clarifying what these medications can and cannot achieve within UK clinical practice

Chemically, it is a modified version of GLP-1 with an amino acid sequence that enhances its stability and prolongs its activity, allowing for less frequent dosing

Key clinical wins : In 2024, Lilly announced new clinical trial results (e.g., further cardiovascular outcome benefits with tirzepatide), which have bolstered prescriber confidence