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Overview of glucagon-like peptide-1 and its role in glucose metabolism New-generation antidiabetic agents, particularly those targeting the glucagon-like peptide-1 (GLP-1) pathway, represent a significant advancement in the treatment of type 2 diabetes

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Diabetes 44, 14655.e2

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Lean mass includes muscle, water, connective tissue, and other non-fat tissue

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Instead, only activation of Oxtr -containing neurons, exclusively intestinal IGLEs that detect stretch, potently suppressed food intake, while various subtypes of mucosal ending neurons, which are classically thought to sense gut peptides, had no effect 28

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