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Retatrutide is a novel synthetic peptide designed as a triple agonist, targeting GLP-1, GIP, and glucagon receptors

Diabetes drug Ozempic is making waves again, this time for a side effect of causing unexpected pregnancies even among women who are on birth control pills.

As a key regulator of glucose levels, GLP-1 helps the body release insulin in

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For clinicians and patients, this is a moment of transition

The mouse models included lean mice (C57BL/6J and NSY.B6- a / a ), obese diabetic mice (NSY.B6- Ay / a ), proglucagon-deficient mice ( Gcg -/-), glucose-dependent insulinotropic polypeptide (GIP) receptor-deficient mice ( Gipr -/-), and ATP-sensitive potassium channel (KATP channel)-deficient mice ( Kcnj11 -/-)