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First, the paucity of large-scale, well-powered druggene interaction studies limits our understanding of the complex genotypephenotype relationships underpinning incretin-based therapies

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J Clin Endocrinol Metab (2002) 87:2404.10.1210/jcem.87.1.8129 27 Perez-TilveDGonzalez-MatiasLAlvarez-CrespoMLeirasRTovarSDieguezCet alExendin-4 potently decreases ghrelin levels in fasting rats

NaB is a GLP-1 sensitizer and represents a potential therapeutic adjuvant to prevent NAFL progression to NASH