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.GLP-1R, GIPR, GCGR insulin/GCG , glucose metabolism,

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However, there was no significant difference in adverse CVEs or all-cause mortality when compared with those taking SGLT2 inhibitors

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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1