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Holistic Approach: The practice emphasizes a holistic view of health, considering all aspects of a patients lifestyle and well-being in the treatment plan

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52,53 Orforglipron, an oral nonpeptide GLP-1 receptor agonist, was also observed to demonstrate weight loss results similar to those observed with injectable GLP-1 receptor agonists in a phase 2 trial, with ongoing studies evaluating the efficacy of orforglipron on weight loss and cardiovascular outcomes (Table 3)

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FIGURE 4 3.4 AE signal detection results To evaluate the potential risk of cholecystitis and cholelithiasis induced by GLP-1 RAs, we utilized three methods, including ROR, PRR, and BCPNN, to detect and conduct a comprehensive analysis of AE signals