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These medications are highly effective but come with a unique profile of adverse effects that affect multiple organ systems and present important considerations for emergency clinicians
Copyright: 2025, Cooper et al

As mentioned earlier, semaglutide GLP-1 tends to produce more significant weight loss compared to liraglutide

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Additionally, if the FDA approves more uses for these medicines, insurance companies will be less likely to object to prescribing GLP-1s for uses beyond diabetes and weight loss

The weight loss achieved with GLP-1 therapy appears central to hepatic benefits, as weight reduction of 710% consistently improves NAFLD across multiple intervention studies
