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Based on studies in non-diabetics with obesity, or overweight plus a weight-related condition, with diet and exercise

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Among higher-income homes, the drop was even steeper at more than 8%

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In a head-to-head competition of diet/exercise versus semaglutide, after 16 months, overweight patients following diet/exercise alone lost 2% of their weight, but semaglutide users lost 20%

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