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A 2026 meta-analysis published in eClinicalMedicine found that weight regain plateaus at 75.3% of weight lost after GLP-1 medication cessation , and discontinuation rates are high

Data availability All numerical source data underlying Figs

Reduced Pleasure From Food For some individuals, favourite foods may feel less appealing while using GLP-1 medications

doi: 10.4161/isl.1.3.9645

Prevalence of metabolic syndrome among adult population of South India: A multistage systematic random sampling approach.International Journal of Medical and Pharmaceutical Research,61122-1129 4.Marzolla, V., Gorini, S., Caprio, M., & Infante, M
