sermorelin and tirzepatide reddit 1 Year Journey From Being a Slob on TRT & Sermorelin : r/moreplatesmoredates June 8, 2026: Reckless physicians
Description
Notable interactions: insulin (hypoglycemia risk), sulfonylureas (hypoglycemia risk), warfarin (altered absorption and possible INR changes), levothyroxine (reduced absorption), and oral contraceptives (modest absorption changes that dont usually affect efficacy)

Wharton et al., 2025 Differentiating with Proven Cardiovascular Benefits: Novo Nordisk is strategically leveraging its extensive clinical data to establish semaglutide as the GLP-1 with the most robust cardiovascular credentials

Reduced Risk of Cardiovascular Events: It can reduce the risk of having strokes and heart attacks

People who dont respond as noticeably are usually compensating through increased appetite without realizing it
Randomised controlled trials have shown that Wegovy can lead to an average weight loss of around 16% after one year

Li W et al
