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Compared with nonusers, adults taking GLP-1s had a: 17 percent lower risk of venous thromboembolism, or blood clots in the veins 31 percent lower risk of pulmonary embolism, a potentially life-threatening clot that travels to the lungs 21 percent lower risk of going to the emergency department 44 percent lower risk of all-cause mortality (death from any cause) Researchers also observed lower stroke rates among GLP-1 users, although this difference didnt reach statistical significance

These findings highlight the potential clinical importance of achieving and maintaining weight loss after GLP-1-based treatment initiation. Meeting: European Congress on Obesity 2026 (ECO2026) Never miss a breakthrough: Join the SciTechDaily newsletter
Patients with contraindications to GLP-1 agonists may explore older weight-loss medications like phentermine or orlistat, or consider non-pharmacologic approaches like intensive lifestyle modification and bariatric surgery consultation
Potential Health Risks Pancreatitis Both medications have been associated with an increased risk of pancreatitis
This review also highlights the existing queries and evidence gaps in DPP-4 inhibitor research

Waterman and D
