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These drugs are FDA-approved for type 2 diabetes and obesity, but growing evidence supports their use for rheumatoid arthritis, psoriatic arthritis, lupus, osteoarthritis, and metabolic/autoimmune diseases. Who should not take GLP-1 medications

This scaffolding allows GPCRs to maintain signaling even when G-protein activity is disabled [61]

Patients taking GLP-1 medications should consult their healthcare provider before initiating magnesium supplementation, particularly if they have underlying medical conditions or are taking other medications

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**Gallbladder Disease**: Some studies have found an increased risk of gallbladder problems, including gallstones, in patients taking GLP-1 agonists and dual agonists

Co-pays: Half of covered patients have a co-pay of $50/mo or less