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[71], there are many research targets for effective pharmacological therapy against NASH

And in 2021, the results from a series of five STEP trials (Semaglutide Treatment Effect in People with obesity) demonstrated marked weight loss even in individuals without type 2 diabetes (T2DM): Phase 3, for example, showed an average loss of about 15 percent over 68 weeks, more than double achieved by any prior obesity drug

This has really helped me stay more regular with my bowels and has really reduced my bloating

The FDA-approved prescribing information for both semaglutide and tirzepatide specifically notes that they delay gastric emptying, which contributes to reduced appetite and caloric intake