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In this study, obese men underwent an initial 8-week low-calorie diet (very low calorie, ~800 kcal/day), losing on average 16.5 kg (about 15% of body weight) pubmed.ncbi.nlm.nih.gov

Udayappan, S., et al

Suspected adverse reactions should be reported via the MHRA Yellow Card scheme
Takeaway: Hair shedding is typically linked to nutritional and metabolic changes during weight loss, not a direct effect of the medication itself
The risk of systemic complications was lower across several parameters (HR 0.320.71)
While current guidelines are clear regarding the benefits of GLP-1 RAs in patients with T2D, there is less clarity about how to adjust background therapies when initiating a GLP-1 RA
