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In 2023, Pfizer terminated the clinical development of two oral GLP-1 small molecule agonists, Lotiglipron and Danuglipron

Patients in 50 states can access personalized care entirely online, with medication shipped directly to their homes

[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Zhang T.J., Qiu Y., Hua Z

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A case series published in late 2025 in SAGE Open Medical Case Reports by Tinsley (Texas Tech University) and Nadolsky (Vineyard Health) provides the first detailed published body composition trajectories from a virtual obesity medicine practice that emphasizes structured resistance training and protein targets alongside incretin therapy

The market growth is driven by drugs with increasing potency to induce weight loss, more convenient oral formulations that help drive adoption as well as increasing interest from non-obese patients looking for weight loss alternatives to diet & exercise