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74 Besides the expected improvements in metabolism and hepatic steatosis, liver fibrosis markers, including the fibrosis-4 index, ferritin, and type IV collagen 7s, were observed to decrease after 24 weeks of treatment

The main adverse events were transient nausea and vomiting

Market Reaction As the company cut its outlook on July 29, 2025, the stock fell from a prior close of $69.00 per share on July 28 to $53.94 per share on July 29, a one-day decline of about 21.83%

Its pharmacological actions on glucose metabolism involve the LKB1-AMPK pathway, which appears to activate ataxia-telangiectasia mutants and activation-induced cytidine deaminase (ATM) [20]

Close supervision from your healthcare provider is critical to understanding and managing any side effects you might experience