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SGLT2 inhibitors could block the reabsorption of glucose in the kidneys, leading to increased glucose excretion and improved glycemic control in type 2 diabetes

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56 After 3 years, the primary composite outcome (nonfatal myocardial infarction, nonfatal stroke, or CV death) occurred in fewer patients assigned to the SGLT2-I versus placebo (10.5% vs 12.1%

For women, especially, they often involve complex hormonal shifts