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In vitro receptor binding studies data have shown SAR425899 to bind to the GCGR 11,14

Additional complications reported include acute kidney injury caused by dehydration from severe gastrointestinal issues such as vomiting and diarrhea

[DOI] [PubMed] [Google Scholar] 54.Gelling RW, et al

Figure 14

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According to the BNF, the typical adult oral dose is 100 mg twice daily (up to 100 mg three times daily if needed), with a maximum of 500 mg daily