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Keywords: Obesity/overweight, Tirzepatide, Type 2 diabetes Key Summary Points Introduction Tirzepatide is a long-acting glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (GIPRA) and glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA)

Protocol for a randomised, double-blinded, placebo-controlled, double-dummy 6-week clinical trial comparing the treatment effects of the glucagon-like peptide 1 receptor agonist liraglutide versus the bile acid sequestrant colesevelam on bile acid malabsorption

The team analyzed electronic health records of 606,434 U.S

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In comparison to other antihyperglycaemic agents, DPP-4 inhibitors lowered total cholesterol slightly more than other agents (total cholesterol 0.18 [0.29