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This highlights a gap in the research, as PsA has been less extensively studied with GLP-1RAs, and further studies are needed to confirm whether GLP-1RAs provide similar immunomodulatory and metabolic benefits in PsA as they do in PsO

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CORRECTION (Oct

The rationale is that fasting-induced hormonal shifts (higher GLP-1, altered ghrelin, improved insulin sensitivity) may synergize with medication-delivered GLP-1 for amplified effect

Estrogen plays a critical role in maintaining muscle mass, bone density, and recovery

In the case of obesity, the weight loss effects dont come from the gut but originate in the brain