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Thomsen L, Gurevich L

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Am Heart J 1(227):5663 Chioncel O, Lainscak M, Seferovic PM, Anker SD, Crespo-Leiro MG, Harjola VP et al (2017) Epidemiology and one-year outcomes in patients with chronic heart failure and preserved, mid-range and reduced ejection fraction: an analysis of the ESC Heart Failure Long-Term Registry

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Both are heterogeneous populations with some overlap

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Accordingly, the degree of DPP-4 inhibition attained in vivo is sufficient to increase circulating levels of intact (active) incretins by 2- to 4-fold and result in improved glycaemic control (118)

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