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Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR

It remains an investigational compound in Phase 3 clinical development
It also inhibits nuclear factor-kappa B (NF-B), a key mediator of inflammation

Preliminary data suggest that -Hydroxy--methylbutyrate may attenuate lean mass loss during caloric restriction [54]

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