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Its primary endpoint, cerebral glucose metabolism, was negative (difference -0.17, P = 0.14)

Acute pancreatitis is a recognised side effect associated with their use

doi: 10.1210/en.2005-0396

Cohort entry was defined as the date of the first-ever prescription for one of the drugs of interest (GLP-1RAs, SGLT2 inhibitors, metformin or other second- or third-line glucose-lowering drugs) during the study period, and their respective first exposure was defined as the index event