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Slowing titration or pausing dose increases for a few weeks can restore balance

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The 10mg/ml concentration requires splitting into two injections

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Key secondary objectives will be to demonstrate the superiority of tirzepatide 5 mg and/or MTD compared to placebo in: (1) maintaining 80% of the body weight reduction achieved during the 60week weightloss period and (2) maintaining 15% body weight reduction for participants who have already lost 15% body weight at randomization (Week 60) including only participants who reached the body weight plateau by the end of the weightloss period (Week 60)

Most weight loss medications only come in a weekly self-administered injection, which can prevent some from ever considering a prescription