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Ongoing Monitoring & Adjustments Follow-up appointments allow for safe dose optimization and long-term success

References 1 Cell Metabolism (2015)The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance (Lee C, Zeng J, Drew BG, et al.)

The product's high structural fidelity makes it an optimal candidate for simulation of endogenous incretin activity under laboratory conditions

Although a prospective cohort study [110] and a recently published randomized controlled trial [105] provided robust evidence of clinical benefits deriving from the use of semaglutide in adult T1D patients, it is worth specifying that the other studies examined in the present review are retrospective observational studies, post-hoc analyses, case series and case reports, which evaluated the impact of the off-label use of semaglutide and tirzepatide in patients with T1D and LADA within a real-world context