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That was the spark for Pep AI
Genetics 201:167184
The recognition that ligands can differentially bias receptor signaling toward distinct intracellular pathways has reframed how efficacy and toxicity are understood
What we do know is that estrogen in particular and possibly some other hormones, but estrogen for sure drives the growth of many cancers, he says
The same precursor is differentially cleaved by two prohormone convertases depending on the tissue context
They are not a sign that something is wrong
