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It also induces glycolysis by stimulating the translocation of glucose transporters GLUT1 and GLUT4 and by activating the AMP-activated protein kinase (AMPK) pathway [63,64,67]

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We nevertheless observed, by RICCS analysis, a tendency for reduced co-diffusion of Laurdan with GLP-1R V229A under vehicle conditions, an effect normally only present in stimulated conditions for WT receptor, with no further change after agonist stimulation observed for the V229A mutant, suggesting a different pattern of interaction of V229A versus WT GLP-1R with plasma membrane lipids

Results vary based on individual response

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