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GLP-1 receptor agonists demonstrate proven efficacy with 1.8% HbA1c reduction and 6.1kg weight loss in clinical trials Approved peptide drugs show favourable safety profiles, but unregulated products pose contamination risks, with purity ranging from 1.7% to 100% Regulatory compliance varies significantly: the FDA classifies peptides as drugs, whilst WADA prohibits many peptides in competitive sport
FDA-approved semaglutide is covered only for treating type 2 diabetes not for prediabetes or diabetes prevention

Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background
In fact, I am enjoying sports now more than ever
