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Additionally, GLP-1 therapies suppress glucagon, a hormone that normally elevates blood sugar, further enhancing glucose regulation

Christopher Sparrow, MD, is an Advanced heart failure cardiologist with OSF HealthCare

GLP-1 analogue CJC-1131 prevents amyloid protein-induced impirments of spatial memory and synaptic plasticity in rats

They also prioritize GLP-1 RAs for patients in whom weight loss is desired or hypoglycemia avoidance is a concern
Mechanistic pathways GLP-1 receptors are expressed in multiple tissues relevant to cardiovascular and renal physiology, including the kidneys, vasculature, and nervous system
Rare but serious risks involve pancreatitis and gallbladder disease
