mechanism of action of glp 1 agonist Mechanisms GLP-1RA Glucagon-like peptide 1 receptor agonists:

Cheng C-L, Lee C-H, Chen P-S, Li Y-H, Lin S-J, Yang Y-HK (2014) Validation of acute myocardial infarction cases in the national health insurance research database in Taiwan

In addition, preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal (HPG) axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, concern new aspects in PCOS which are probably not always related to weight loss

Front Aging Neurosci 2016

PMID: 35985340.

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While the observed associations do not establish causality, they highlight the importance of vigilance for potential NAEs during treatment, particularly given the heterogeneous temporal patterns of onset across events