![glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fnrendo.2012.140/MediaObjects/41574_2012_Article_BFnrendo2012140_Fig1_HTML.jpg)
glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]
Description
2 Glucagon-like peptide-1 receptor (GLP-1R) agonists have shown remarkable therapeutic effects for type 2 diabetes mellitus (T2DM)
![glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://tmedweb.tulane.edu/pharmwiki/lib/exe/fetch.php/glp1_ra_infographic.png)
That does not exclude GLP 1 therapy for individuals with obesity or metabolic issues under medical supervision
![glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://www.frontiersin.org/files/Articles/1085799/xml-images/fendo-14-1085799-g001.webp)
This medication has a broad range of effects because it can attach to different receptors
![glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://www.researchgate.net/profile/Ilaria-Dicembrini/publication/281057215/figure/fig1/AS:271833661480964@1441821603511/Physiology-of-GLP-1-secretion-and-action-on-GLP-1-receptors-in-different-organs-and.png)
Clinicians are also cautious about prescribing these drugs to individuals with a history of eating disorders, where appetite suppression and weight loss may trigger relapse
![glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://www.optimaldx.com/hs-fs/hubfs/image-png-May-05-2025-06-34-15-1242-PM.png?width=975&height=504&name=image-png-May-05-2025-06-34-15-1242-PM.png)
Rapid heart rate
![glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://www.researchgate.net/publication/363201315/figure/fig1/AS:11431281082644832@1662084797872/Amino-acid-sequences-of-the-incretin-hormones-GLP-1-glucagon-like-peptide-1-and-GIP.png)
Reduced Incretin Effect in Type 2 Diabetes
![glp-1 receptor agonist natural agonists for individualized treatment of type 2 diabetes mellitus glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://lookaside.instagram.com/seo/google_widget/crawler/?media_id=3938352351080990713)
